There are several reasons why IVF (In vitro fertilization) may fail repeatedly, including:
- Implantation issues: Embryo implantation in the uterine lining can be disrupted due to issues such as endometrial thickness, endometrial receptivity, and uterine abnormalities.
- Chromosomal abnormalities: A high number of embryos with chromosomal abnormalities can result in repeated IVF failure.
- Age: As a woman ages, her egg quality and quantity decrease, making it harder for the eggs to fertilize and implant successfully.
- Ovarian reserve: A low level of follicle-stimulating hormone (FSH) can indicate poor ovarian reserve, leading to difficulty producing enough eggs for successful IVF.
- Male factor infertility: Issues with the sperm, such as low sperm count, motility or morphology, can impact the success of IVF.
- Lifestyle factors: Smoking, obesity, and stress can negatively impact the success of IVF.
The Clinic has to play special attention to
- Choose the right egg : Declining oocyte quality with age, leading to chromosomal abnormalities in the embryo due to damage to the oocyte’s spindle apparatus
- Choose the right sperm at right time ” Poor sperm quality, which can prevent fertilization or the ability of the sperm to penetrate the egg’s outer shell
- Selection of an abnormal embryo, which the uterus may reject
- Clear the issues in the uterus, such as hormonal imbalances, structural problems, or a thin endometrium, that can impact the success of the IVF cycle
- Oversee and consult the lifestyle of both partners, including drug, tobacco, and alcohol use, as well as medical conditions like hypertension, diabetes, and blood clotting disorders
- Incorrect timing or placement of the embryo during the transfer procedure
